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Failure of traditional therapies like metformin Coexisting obesity or type 2 diabetes Severe hyperandrogenism or menstrual irregularities Essential Pre-Treatment Screening Before starting any new treatment, a thorough medical screening is non-negotiable

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Long-chain fatty acids and phospholipids like lysophosphatidylcholine (LPC), other compounds such as retinoic acid (RA) and multiple N-acylethanolamines (NAE) such as N-oleyldopamine (OLDA), palmitoylethanolamide (PEA), or oleylethanolamide (OEA), all act as endogenous ligands of GPR119

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